Ctyl L-Carnitine Nzu otite
1. Okwu Mmalite nke A CTTL L- Carnisine :
Cartyl L-Carnitine na-eji uzo metabolic na-egbochi ụfọdụ enzymes ụfọdụ, nke na-enye ohere maka protein Kinase Amp. Enwere ike ịkọwa nke a ka akwa dị ka nke a: Ozugbo ị were nnukwu Aican oke, ọ na-aghọ aghụghọ gị na ọkwa cellular iji chee na ememe mmega ahụ. Ebe ahụ na-eche na ọ mere ka ọ bụrụ ihe mmega ahụ dị ukwuu, ike mgbatị ahụ na-amalite ịtụgharị isi mmalite mmanụ, dị ka abụba acid, iji rụpụta ume nke echekwara n'oge mmega ahụ. Nke a nwere ike inwe mmetụta na-arụ ọrụ na ọkwa ntachi obi na nkwado nke ọrụ ahụ. A na-ahụkwa ụdị mmetụta insulin ka ọ bụrụ otu ihe na-emepụta, dị ka ahụ ga-eche na ọ ga-agafe usoro mmega ahụ. N'ụzọ na-akpali mmasị, na ọmụmụ anụmanụ nke nwere oke ụmụ oke, ma ihe oriri na-abaghị uru ụmụ oke, ma ihe ọ bụla na-adịghị mma na-erite uru insulin ma ọ bụ mmụba na Glucose. Na-ekwu, ngwa ahụ na iwepụ aka adịghị mma, dịka usoro a na-eche maka ọdịdị na ibu, ahụrụ m ihe kpatara iji iji Aicar. Nhọrọ kachasị mma ga-abụ catarine (GW-50156), dị ka onyinye a na-emegharị site na mmega ahụ, yabụ mkpa ọ ga-arụ ma ọ bụ cardio ga-abụ ihe mkpali.
2 . Ozi nkiti :
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Product Name
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Acetyl l-carnitine Powder
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Specification
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98.5%~99.3%
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Appearance
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White crystal powder
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Mesh
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80 mesh
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Molecular formula
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C4H9N02
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Molecular weight
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103.1
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CAS No
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56-12-2
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Flow Chart
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Synthesis、Microbial fermentation
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Solubility
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have aqueous disintegration, soluble in water, slightly soluble in hot ethanol, insoluble in cold ethanol, diethyl ether and benzene;
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3 . Ọrụ nke Ctyl L-Carnitine Ntụ ntụ:
A CANTL L-Carnitine bụ anasog analog nke na-arụ ọrụ na protein protein amp - ampk). Ampk na-achịkwa lipid na glucose metabolism iji dozie ike cellostasis (Hadie na curling).
A na- eji ntụ ntụ Cartyl l-carnitine nwere ike igwu aka na ịkwalite usoro ndị a n'ihi na o nwere ikike ịbanye na mkpụrụ ndụ cell ma gbochie mmepụta enzymesin iji dozie glucose na nchụpụ ume. Site na enzymes nchịkwa ndị a gbochiri, mkpụrụ ndụ ndị ahụ metụtara na-eme ka ọnụọgụ glucose nke a ga-anata, ọ nwekwara ike ịmụrụ ntụgharị nke ike ya. Ọzọkwa, kpebisiri ike ịnọgide na Peptide nke Peptide iji nyere aka n'ịdị ala, usoro a na-akpọkwa apoptosis.
4. Ngwa:
(1) A na-eji ntụ ntụ Cartyl l-carnitine etinyere na ubi Phamacetical, a na-eji ya eme ihe dị ka ihe na-eme ka ihe ọ bụla ghara imerụ ahụ, na-efe efe, na-efe efe na ndị na-eli ozu.
(2) A na-eji ntụ ntụ na-etinye na mpaghara ahụike, a na-eji ya na ngwaahịa ahụike iji zụlite ụbụrụ, chebe imeju ma melite oke ụra.
(3) Aicar etinyere na mpaghara ịchọ mma, a na-eji kwalite metabolism anụ ma mee ka akpụkpọ ahụ dị nro ma sie ike.
5 .
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Item
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Specification
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Method
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Identification
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In accordance with the IR absorption spectrum of the standard
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IR
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Appearance
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White Crystals or White
Crystalline Powder
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Visual
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Specific rotation
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-29.0~-32.0°
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USP
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PH
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5.5~9.5
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USP
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Water
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≤4.0%
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USP
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Residue on ignition
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≤0.5%
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USP
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Residual solvents
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≤0.5%
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USP
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Sodium
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≤0.1%
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USP
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Potassium
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≤0.2%
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USP
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Chloride
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≤0.4%
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USP
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Cyanide
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Non detectable
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Ch.P.
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Heavy metal
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≤10ppm
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USP
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Arsenic (As)
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≤1ppm
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USP
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Lead (Pb)
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≤3ppm
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USP
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Cadmium (Cd)
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≤1ppm
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USP
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Mercury (Hg)
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≤0.1ppm
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USP
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TPC
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≤1000Cfu/g
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USP
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Yeast & Mold
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≤ 100Cfu/g
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USP
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E.Coli
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Negative
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USP
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Salmonella
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Negative
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USP
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Assay
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98.0~102.0%
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Titration
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bulk density
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0.3-0.6g/ml
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Physical
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Tapped density
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0.5-0.8g/ml
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Physical
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