A na-akpọkwa Alfa-Ketoglutate Ketoglutaric acid (α-Ketoglutaric acid), otu n'ime mkpụrụ osisi chetor nke glutaric nke glutaric acid, na-acha ọcha kristal. Nnu ya bụ onyinye dị mkpa ndu. α-Ketoglutaric acid na-ekere òkè na usoro acciaxylic, ma na-ekeresi ike nke amino acid, vitamin na metabolism ike. Enwere ike iji ya mee ihe dị ka mgbakwunye njikere nri, nweekwa ụdị atụmanya ngwa.
Ọrụ ngwa
Tricaarboxylic acid
α-Ketoglutate bụ ihe dị mkpa metabolic intermediate na tricarboxylic acid okirikiri nke microorganisms microorganis, ọ bụ ihe dị mkpa na-ejikọ metabolism carbon-nitrogen. Ọ dị mgbe acidcid acid na tupu sucyll coamyme a na okirikiri. Na saịtị a, mmeghachi omume na-eme ka a nwee ike nweta metabolite a site na mmepụta nke autoglutate site na ndọtị nke glutamate dehydrogenase na glutamate. [2]
Ọgbọ nke amino acid
A na-emepụta glutamate site na Sintamine Sintamine na-emepụta, nke na-eji mololu nke ATP iji mepụta phosphyl phosphate; Ammonia wakporo etiti a, nke na-eme dị ka onye recopophilic regrent, nke na-ebute nguzo nke glutamine na intorenic phosnate.
Nri nri
A na-ere Alfa-Ketoglutate dị ka ihe mgbakwunye nri ndị ọzọ AKG ma ọ bụ na-ahụ maka ndị na-anụ ọkụ n'obi ma ọ bụ anụ ahụ, ndị na-ekwu na ihe ndị ahụ na-eme ka ọ na-arụ ọrụ na ọnụ ọgụgụ kachasị elu. A na-ekwu na ọ dabere na "Nchọpụta na-egosi na amonia nwere ike na-ekekọta Alfa-Ketoglutate ma mee ka ewepu ọtụtụ nsogbu na-emekọ ihe na-egbu egbu". Agbanyeghị, naanị ihe ọmụmụ gosipụtara Alfa-KetogLutate ka ọ dị irè na ibelata ihe na-egbu egbu na-ebelata ndị ọrịa amsodialysis.
Ketoglutaric acid calcilus (alfa Ketoglutaric acid) bụ etiti etiti site na np ma ọ bụ gtp na okirikiri krebs. 2-Ketoglutaric Acid call na-arụ ọrụ dị ka akwa carbon nke na-eme ka mmeghachi omume nitrogen. 2-Ketoglutaric acid calcium bụ ihe na-agbanwe agbanwe nke tiyyosinase (IC50 = 15 mm).
Nkọwa nke ngwaahịa
Aha ngwaahịa: Calcium Alfa Ketoglutate
Enweghị .: 71686-01-6
Molecular usoro: C5H8CAO5
molular ibu: 188.19
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